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Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons
Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder caused by the selective loss of the upper and lower motor neurons. Only 10% of all cases are caused by a mutation in one of the two dozen different identified genes, while the remaining 90% are likely caused by a combina...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826239/ https://www.ncbi.nlm.nih.gov/pubmed/29515358 http://dx.doi.org/10.3389/fnins.2018.00086 |