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Extreme heterogeneity of influenza virus infection in single cells
Viral infection can dramatically alter a cell’s transcriptome. However, these changes have mostly been studied by bulk measurements on many cells. Here we use single-cell mRNA sequencing to examine the transcriptional consequences of influenza virus infection. We find extremely wide cell-to-cell var...
Autores principales: | Russell, Alistair B, Trapnell, Cole, Bloom, Jesse D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826275/ https://www.ncbi.nlm.nih.gov/pubmed/29451492 http://dx.doi.org/10.7554/eLife.32303 |
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