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Peripheral Etanercept Administration Normalizes Behavior, Hippocampal Neurogenesis, and Hippocampal Reelin and GABA(A) Receptor Expression in a Preclinical Model of Depression

Depression is a serious psychiatric disorder frequently comorbid with autoimmune disorders. Previous work in our lab has demonstrated that repeated corticosterone (CORT) injections in rats reliably increase depressive-like behavior, impair hippocampal-dependent memory, reduce the number and complexi...

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Detalles Bibliográficos
Autores principales: Brymer, Kyle J., Fenton, Erin Y., Kalynchuk, Lisa E., Caruncho, Hector J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826281/
https://www.ncbi.nlm.nih.gov/pubmed/29515447
http://dx.doi.org/10.3389/fphar.2018.00121