Spatial structure of disordered proteins dictates conductance and selectivity in nuclear pore complex mimics

Nuclear pore complexes (NPCs) lined with intrinsically disordered FG-domains act as selective gatekeepers for molecular transport between the nucleus and the cytoplasm in eukaryotic cells. The underlying physical mechanism of the intriguing selectivity is still under debate. Here, we probe the trans...

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Detalles Bibliográficos
Autores principales: Ananth, Adithya N, Mishra, Ankur, Frey, Steffen, Dwarkasing, Arvind, Versloot, Roderick, van der Giessen, Erik, Görlich, Dirk, Onck, Patrick, Dekker, Cees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826291/
https://www.ncbi.nlm.nih.gov/pubmed/29442997
http://dx.doi.org/10.7554/eLife.31510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826291/
https://www.ncbi.nlm.nih.gov/pubmed/29442997
http://dx.doi.org/10.7554/eLife.31510

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