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Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

The adaptive immune system recognizes antigens via an immense array of antigen-binding antibodies and T-cell receptors, the immune repertoire. The interrogation of immune repertoires is of high relevance for understanding the adaptive immune response in disease and infection (e.g., autoimmunity, can...

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Detalles Bibliográficos
Autores principales: Miho, Enkelejda, Yermanos, Alexander, Weber, Cédric R., Berger, Christoph T., Reddy, Sai T., Greiff, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826328/
https://www.ncbi.nlm.nih.gov/pubmed/29515569
http://dx.doi.org/10.3389/fimmu.2018.00224