High-Throughput Sequencing of the Expressed Torafugu (Takifugu rubripes) Antibody Sequences Distinguishes IgM and IgT Repertoires and Reveals Evidence of Convergent Evolution

B-cell antigen receptor (BCR) or antibody diversity arises from somatic recombination of immunoglobulin (Ig) gene segments and is concentrated within the Ig heavy (H) chain complementarity-determining region 3 (CDR-H3). We performed high-throughput sequencing of the expressed antibody heavy-chain re...

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Detalles Bibliográficos
Autores principales: Fu, Xi, Sun, Jianqiang, Tan, Engkong, Shimizu, Kentaro, Reza, Md Shaheed, Watabe, Shugo, Asakawa, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826340/
https://www.ncbi.nlm.nih.gov/pubmed/29515575
http://dx.doi.org/10.3389/fimmu.2018.00251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826340/
https://www.ncbi.nlm.nih.gov/pubmed/29515575
http://dx.doi.org/10.3389/fimmu.2018.00251

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