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Triclosan Enhances the Clearing of Pathogenic Intracellular Salmonella or Candida albicans but Disturbs the Intestinal Microbiota through mTOR-Independent Autophagy

Triclosan (TCS) is a broad-spectrum antimicrobial agent, whose well-known antibacterial mechanism is inhibiting lipid synthesis. Autophagy, an innate immune response, is an intracellular process that delivers the cargo including pathogens to lysosomes for degradation. In this study, we first demonst...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Yu, Zhongyang, Shi, Xiaochen, Tang, Xudong, Wang, Yang, Wang, Xueyan, An, Yanan, Li, Shulin, Li, Yan, Wang, Xuefei, Luan, Wenjing, Chen, Zhaobin, Liu, Mingyuan, Yu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826388/
https://www.ncbi.nlm.nih.gov/pubmed/29515975
http://dx.doi.org/10.3389/fcimb.2018.00049