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Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders

Mounting evidence suggests that the guanine-based purines stand out as key player in cell metabolism and in several models of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. Guanosine (GUO) and guanine (GUA) are extracellular signaling molecules derived from the breakdown...

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Detalles Bibliográficos
Autores principales: Zuccarini, Mariachiara, Giuliani, Patricia, Frinchi, Monica, Mudò, Giuseppa, Serio, Rosa Maria, Belluardo, Natale, Buccella, Silvana, Carluccio, Marzia, Condorelli, Daniele F., Caciagli, Francesco, Ciccarelli, Renata, Di Iorio, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826394/
https://www.ncbi.nlm.nih.gov/pubmed/29515443
http://dx.doi.org/10.3389/fphar.2018.00110