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Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders
Mounting evidence suggests that the guanine-based purines stand out as key player in cell metabolism and in several models of neurodegenerative disorders, such as Parkinson’s and Alzheimer’s diseases. Guanosine (GUO) and guanine (GUA) are extracellular signaling molecules derived from the breakdown...
Autores principales: | Zuccarini, Mariachiara, Giuliani, Patricia, Frinchi, Monica, Mudò, Giuseppa, Serio, Rosa Maria, Belluardo, Natale, Buccella, Silvana, Carluccio, Marzia, Condorelli, Daniele F., Caciagli, Francesco, Ciccarelli, Renata, Di Iorio, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826394/ https://www.ncbi.nlm.nih.gov/pubmed/29515443 http://dx.doi.org/10.3389/fphar.2018.00110 |
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