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Carnitine Palmitoyltransferase 1A Has a Lysine Succinyltransferase Activity

Lysine succinylation was recently identified as a post-translational modification in cells. However, the molecular mechanism underlying lysine succinylation remains unclear. Here, we show that carnitine palmitoyltransferase 1A (CPT1A) has lysine succinyl-transferase (LSTase) activity in vivo and in...

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Detalles Bibliográficos
Autores principales: Kurmi, Kiran, Hitosugi, Sadae, Wiese, Elizabeth K., Boakye-Agyeman, Felix, Gonsalves, Wilson I., Lou, Zhenkun, Karnitz, Larry M., Goetz, Matthew P., Hitosugi, Taro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826573/
https://www.ncbi.nlm.nih.gov/pubmed/29425493
http://dx.doi.org/10.1016/j.celrep.2018.01.030