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Inflammatory Cytokines Stabilize SOXC Transcription Factors to Mediate the Transformation of Fibroblast‐Like Synoviocytes in Arthritic Disease

OBJECTIVE: Fibroblast‐like synoviocytes (FLS) produce key synovial fluid and tissue components to ensure joint integrity under healthy conditions, whereas they become cancer‐like and aggressively contribute to joint degeneration in inflammatory arthritis. The aim of this study was to determine wheth...

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Detalles Bibliográficos
Autores principales: Bhattaram, Pallavi, Muschler, George, Wixler, Viktor, Lefebvre, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826855/
https://www.ncbi.nlm.nih.gov/pubmed/29193895
http://dx.doi.org/10.1002/art.40386