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Elastic net regularized regression for time-series analysis of plasma metabolome stability under sub-optimal freezing condition
In this paper, the stability of the plasma metabolome at −20 °C for up to 30 days was evaluated using liquid chromatography-high resolution mass spectrometric metabolomics analysis. To follow the time-series deterioration of the plasma metabolome, the use of an elastic net regularized regression mod...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826937/ https://www.ncbi.nlm.nih.gov/pubmed/29483546 http://dx.doi.org/10.1038/s41598-018-21851-7 |