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Neferine Protects Endothelial Glycocalyx via Mitochondrial ROS in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome

Damage to the endothelial glycocalyx is a critical factor in increased pulmonary vascular permeability, which is the basic pathological feature of acute respiratory distress syndrome (ARDS). Neferine (Nef), a bisbenzylisoquinoline alkaloid isolated from green seed embryos of Nelumbo nucifera Gaertn,...

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Detalles Bibliográficos
Autores principales: Liu, Xiang-Yong, Xu, Hai-Xiao, Li, Jian-Kui, Zhang, Dong, Ma, Xiao-Hong, Huang, Li-Na, Lü, Jun-Hong, Wang, Xiao-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826949/
https://www.ncbi.nlm.nih.gov/pubmed/29520236
http://dx.doi.org/10.3389/fphys.2018.00102