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Graphene‐Based MicroRNA Transfection Blocks Preosteoclast Fusion to Increase Bone Formation and Vascularization

The objective of this study is to design a graphene‐based miRNA transfection drug delivery system for antiresorptive therapy. An efficient nonviral gene delivery system is developed using polyethylenimine (PEI) functionalized graphene oxide (GO) complex loaded with miR‐7b overexpression plasmid. GO‐...

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Detalles Bibliográficos
Autores principales: Dou, Ce, Ding, Ning, Luo, Fei, Hou, Tianyong, Cao, Zhen, Bai, Yun, Liu, Chuan, Xu, Jianzhong, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826985/
https://www.ncbi.nlm.nih.gov/pubmed/29619305
http://dx.doi.org/10.1002/advs.201700578