Targeting Ligand Specificity Linked to Tumor Tissue Topological Heterogeneity via Single-Cell Micro-Pharmacological Modeling

Targeted therapy has held promise to be a successful anticancer treatment due to its specificity towards tumor cells that express the target receptors. However, not all targeting drugs used in the clinic are equally effective in tumor eradication. To examine which biochemical and biophysical propert...

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Detalles Bibliográficos
Autores principales: Karolak, Aleksandra, Estrella, Veronica C., Huynh, Amanda S., Chen, Tingan, Vagner, Josef, Morse, David L., Rejniak, Katarzyna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827036/
https://www.ncbi.nlm.nih.gov/pubmed/29483578
http://dx.doi.org/10.1038/s41598-018-21883-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827036/
https://www.ncbi.nlm.nih.gov/pubmed/29483578
http://dx.doi.org/10.1038/s41598-018-21883-z

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