Cargando…
A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets
Exosomal miRNA transfer is a mechanism for cell–cell communication that is important in the immune response, in the functioning of the nervous system and in cancer. Syncrip/hnRNPQ is a highly conserved RNA-binding protein that mediates the exosomal partition of a set of miRNAs. Here, we report that...
Autores principales: | Hobor, Fruzsina, Dallmann, Andre, Ball, Neil J., Cicchini, Carla, Battistelli, Cecilia, Ogrodowicz, Roksana W., Christodoulou, Evangelos, Martin, Stephen R., Castello, Alfredo, Tripodi, Marco, Taylor, Ian A., Ramos, Andres |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827114/ https://www.ncbi.nlm.nih.gov/pubmed/29483512 http://dx.doi.org/10.1038/s41467-018-03182-3 |
Ejemplares similares
-
SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells
por: Riccioni, Veronica, et al.
Publicado: (2022) -
IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties
por: Dagil, Robert, et al.
Publicado: (2019) -
RNA-binding protein syncrip regulates starvation-induced hyperactivity in adult Drosophila
por: Chi, Wanhao, et al.
Publicado: (2021) -
Targeting of polycombs to DNA in EMT
por: Battistelli, Cecilia, et al.
Publicado: (2017) -
Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation
por: Samuels, Tamsin J., et al.
Publicado: (2020)