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A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets

Exosomal miRNA transfer is a mechanism for cell–cell communication that is important in the immune response, in the functioning of the nervous system and in cancer. Syncrip/hnRNPQ is a highly conserved RNA-binding protein that mediates the exosomal partition of a set of miRNAs. Here, we report that...

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Detalles Bibliográficos
Autores principales: Hobor, Fruzsina, Dallmann, Andre, Ball, Neil J., Cicchini, Carla, Battistelli, Cecilia, Ogrodowicz, Roksana W., Christodoulou, Evangelos, Martin, Stephen R., Castello, Alfredo, Tripodi, Marco, Taylor, Ian A., Ramos, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827114/
https://www.ncbi.nlm.nih.gov/pubmed/29483512
http://dx.doi.org/10.1038/s41467-018-03182-3