IMP1 KH1 and KH2 domains create a structural platform with unique RNA recognition and re-modelling properties

IGF2 mRNA-binding protein 1 (IMP1) is a key regulator of messenger RNA (mRNA) metabolism and transport in organismal development and, in cancer, its mis-regulation is an important component of tumour metastasis. IMP1 function relies on the recognition of a diverse set of mRNA targets that is mediate...

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Detalles Bibliográficos
Autores principales: Dagil, Robert, Ball, Neil J, Ogrodowicz, Roksana W, Hobor, Fruzsina, Purkiss, Andrew G, Kelly, Geoff, Martin, Stephen R, Taylor, Ian A, Ramos, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486635/
https://www.ncbi.nlm.nih.gov/pubmed/30864660
http://dx.doi.org/10.1093/nar/gkz136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486635/
https://www.ncbi.nlm.nih.gov/pubmed/30864660
http://dx.doi.org/10.1093/nar/gkz136

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