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Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

During Drosophila and vertebrate brain development, the conserved transcription factor Prospero/Prox1 is an important regulator of the transition between proliferation and differentiation. Prospero level is low in neural stem cells and their immediate progeny, but is upregulated in larval neurons an...

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Detalles Bibliográficos
Autores principales: Samuels, Tamsin J., Arava, Yoav, Järvelin, Aino I., Robertson, Francesca, Lee, Jeffrey Y., Yang, Lu, Yang, Ching-Po, Lee, Tzumin, Ish-Horowicz, David, Davis, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225087/
https://www.ncbi.nlm.nih.gov/pubmed/32205310
http://dx.doi.org/10.1242/bio.049684