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Posttransplant Intramuscular Injection of PLX-R18 Mesenchymal-Like Adherent Stromal Cells Improves Human Hematopoietic Engraftment in A Murine Transplant Model

Late-term complications of hematopoietic cell transplantation (HCT) are numerous and include incomplete engraftment. One possible mechanism of incomplete engraftment after HCT is cytokine-mediated suppression or dysfunction of the bone marrow microenvironment. Mesenchymal stromal cells (MSCs) elabor...

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Detalles Bibliográficos
Autores principales: Metheny, Leland, Eid, Saada, Lingas, Karen, Ofir, Racheli, Pinzur, Lena, Meyerson, Howard, Lazarus, Hillard M., Huang, Alex Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827167/
https://www.ncbi.nlm.nih.gov/pubmed/29520362
http://dx.doi.org/10.3389/fmed.2018.00037