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H19 lncRNA alters methylation and expression of Hnf4α in the liver of metformin-exposed fetuses
Metformin is the most widely used anti-diabetic medication worldwide. However, human and animal studies suggest that prenatal metformin exposure may increase the risk of metabolic disorders in adult offspring, yet the underpinning mechanism remains unclear. Here we report that metformin-exposed mous...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827203/ https://www.ncbi.nlm.nih.gov/pubmed/29215608 http://dx.doi.org/10.1038/cddis.2017.392 |