Proteomic and functional analysis identifies galectin-1 as a novel regulatory component of the cytotoxic granule machinery

Secretory granules released by cytotoxic T lymphocytes (CTLs) are powerful weapons against intracellular microbes and tumor cells. Despite significant progress, there is still limited information on the molecular mechanisms implicated in target-driven degranulation, effector cell survival and compos...

Descripción completa

Detalles Bibliográficos
Autores principales: Clemente, Tiago, Vieira, Narcisio J, Cerliani, Juan P, Adrain, Colin, Luthi, Alexander, Dominguez, Mariana R, Yon, Monica, Barrence, Fernanda C, Riul, Thalita B, Cummings, Richard D, Zorn, Telma M, Amigorena, Sebastian, Dias-Baruffi, Marcelo, Rodrigues, Maurício M, Martin, Seamus J, Rabinovich, Gabriel A, Amarante-Mendes, Gustavo P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827204/
https://www.ncbi.nlm.nih.gov/pubmed/29215607
http://dx.doi.org/10.1038/cddis.2017.506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827204/
https://www.ncbi.nlm.nih.gov/pubmed/29215607
http://dx.doi.org/10.1038/cddis.2017.506

Ejemplares similares