Characterization of the in Vitro Metabolic Profile of Evodiamine in Human Liver Microsomes and Hepatocytes by UHPLC-Q Exactive Mass Spectrometer

Evodiamine is an indoloquinazoline alkaloid isolated from the fruit of Evodia rutaecarpa, which has a wide range of pharmacological effects like anti-tumor and anti-inflammatory effects. This study was intended to investigate the metabolic characteristics of evodiamine in human liver microsomes and...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaowei, Fang, Tianzi, Zhou, Hongyun, Yuan, Jie, Liu, Qingwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827300/
https://www.ncbi.nlm.nih.gov/pubmed/29520234
http://dx.doi.org/10.3389/fphar.2018.00130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827300/
https://www.ncbi.nlm.nih.gov/pubmed/29520234
http://dx.doi.org/10.3389/fphar.2018.00130

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