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A Pilot Study of Tranilast for Cardiomyopathy of Muscular Dystrophy

OBJECTIVE: Heart failure is currently the most serious complication of muscular dystrophy. The transient receptor potential cation channel, subfamily V, member 2 (TRPV2) is a stretch-sensitive Ca channel. In damaged myocytes or cardiomyocytes, TRPV2 translocates to the cytoplasmic membrane and enhan...

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Detalles Bibliográficos
Autores principales: Matsumura, Tsuyoshi, Matsui, Misa, Iwata, Yuko, Asakura, Masanori, Saito, Toshio, Fujimura, Harutoshi, Sakoda, Saburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827307/
https://www.ncbi.nlm.nih.gov/pubmed/29093384
http://dx.doi.org/10.2169/internalmedicine.8651-16