Multidrug Resistance in Cancer Circumvented Using a Cytosolic Drug Reservoir

It is discovered that sustained cytosolic drug release at a sufficient concentration is an effective mechanism to circumvent multidrug resistance and consequently enhance antitumor drug efficacy. It is showed that a simple way to enable this mechanism is to reach an intracellular kinetic balance of...

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Detalles Bibliográficos
Autores principales: Fan, Li, Zhang, Silu, Zhang, Chunyuan, Yin, Chun, Chu, Zhiqin, Song, Chaojun, Lin, Ge, Li, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827467/
https://www.ncbi.nlm.nih.gov/pubmed/29619295
http://dx.doi.org/10.1002/advs.201700289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827467/
https://www.ncbi.nlm.nih.gov/pubmed/29619295
http://dx.doi.org/10.1002/advs.201700289

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