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Overexpression of preeclampsia induced microRNA-26a-5p leads to proteinuria in zebrafish

So far the pathomechanism of preeclampsia in pregnancy is focussed on increased circulating levels of soluble fms-like tyrosin kinase-1 (sFLT-1) that neutralizes glomerular VEGF-A expression and prevents its signaling at the glomerular endothelium. As a result of changed glomerular VEGF-A levels end...

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Detalles Bibliográficos
Autores principales: Müller-Deile, Janina, Schröder, Patricia, Beverly-Staggs, Lynne, Hiss, Rebecca, Fiedler, Jan, Nyström, Jenny, Thum, Thomas, Haller, Hermann, Schiffer, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827519/
https://www.ncbi.nlm.nih.gov/pubmed/29483572
http://dx.doi.org/10.1038/s41598-018-22070-w