Triphenylphosphonium Moiety Modulates Proteolytic Stability and Potentiates Neuroprotective Activity of Antioxidant Tetrapeptides in Vitro

Although delocalized lipophilic cations have been identified as effective cellular and mitochondrial carriers for a range of natural and synthetic drug molecules, little is known about their effects on pharmacological properties of peptides. The effect of triphenylphosphonium (TPP) cation on bioacti...

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Detalles Bibliográficos
Autores principales: Akhmadishina, Rezeda A., Garifullin, Ruslan, Petrova, Natalia V., Kamalov, Marat I., Abdullin, Timur I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827532/
https://www.ncbi.nlm.nih.gov/pubmed/29520232
http://dx.doi.org/10.3389/fphar.2018.00115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827532/
https://www.ncbi.nlm.nih.gov/pubmed/29520232
http://dx.doi.org/10.3389/fphar.2018.00115

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