Donor-Derived Regulatory Dendritic Cell Infusion Maintains Donor-Reactive CD4(+)CTLA4(hi) T Cells in Non-Human Primate Renal Allograft Recipients Treated with CD28 Co-Stimulation Blockade

Donor-derived regulatory dendritic cell (DCreg) infusion before transplantation, significantly prolongs renal allograft survival in non-human primates. This is associated with enhanced expression of the immunoregulatory molecules cytotoxic T-lymphocyte-associated antigen (Ag) 4 (CTLA4) and programme...

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Detalles Bibliográficos
Autores principales: Ezzelarab, Mohamed B., Lu, Lien, Shufesky, William F., Morelli, Adrian E., Thomson, Angus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827543/
https://www.ncbi.nlm.nih.gov/pubmed/29520267
http://dx.doi.org/10.3389/fimmu.2018.00250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827543/
https://www.ncbi.nlm.nih.gov/pubmed/29520267
http://dx.doi.org/10.3389/fimmu.2018.00250

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