Alloreactive T Cell Receptor Diversity against Structurally Similar or Dissimilar HLA-DP Antigens Assessed by Deep Sequencing

T cell alloreactivity is mediated by a self-human leukocyte antigen (HLA)-restricted T cell receptor (TCR) repertoire able to recognize both structurally similar and dissimilar allogeneic HLA molecules (i.e., differing by a single or several amino acids in their peptide-binding groove). We hypothesi...

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Detalles Bibliográficos
Autores principales: Arrieta-Bolaños, Esteban, Crivello, Pietro, Metzing, Maximilian, Meurer, Thuja, Ahci, Müberra, Rytlewski, Julie, Vignali, Marissa, Yusko, Erik, van Balen, Peter, Horn, Peter A., Falkenburg, J. H. Frederik, Fleischhauer, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827552/
https://www.ncbi.nlm.nih.gov/pubmed/29520276
http://dx.doi.org/10.3389/fimmu.2018.00280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827552/
https://www.ncbi.nlm.nih.gov/pubmed/29520276
http://dx.doi.org/10.3389/fimmu.2018.00280

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