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Beyond Enumeration: Functional and Computational Analysis of Circulating Tumor Cells to Investigate Cancer Metastasis

Circulating tumor cells (CTCs) are defined as those cells that detach from a cancerous lesion and enter the bloodstream. While generally most CTCs are subjected to high shear stress, anoikis signals, and immune attack in the circulatory system, few are able to survive and reach a distant organ in a...

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Detalles Bibliográficos
Autores principales: Castro-Giner, Francesc, Scheidmann, Manuel C., Aceto, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827555/
https://www.ncbi.nlm.nih.gov/pubmed/29520361
http://dx.doi.org/10.3389/fmed.2018.00034