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A Novel Role for C5a in B-1 Cell Homeostasis

B-1 cells constitute a unique subpopulation of lymphocytes residing mainly in body cavities like the peritoneal cavity (PerC) but are also found in spleen and bone marrow (BM). As innate-like B cells, they mediate first line immune defense through low-affinity natural IgM (nIgM) antibodies. PerC B-1...

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Detalles Bibliográficos
Autores principales: Bröker, Katharina, Figge, Julia, Magnusen, Albert F., Manz, Rudolf A., Köhl, Jörg, Karsten, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827565/
https://www.ncbi.nlm.nih.gov/pubmed/29520270
http://dx.doi.org/10.3389/fimmu.2018.00258