Combined Treatment with Valproic Acid and 5-Aza-2′-Deoxycytidine Synergistically Inhibits Human Clear Cell Renal Cell Carcinoma Growth and Migration

BACKGROUND: Histone acetylation and DNA methylation are important mammalian epigenetic modifications that participate in the regulation of gene expression. Because dysregulation of histone deacetylase and DNA methyltransferases are hallmarks of malignancy, they have become promising therapeutic targ...

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Detalles Bibliográficos
Autores principales: Xi, Wenjin, Chen, Xu, Sun, Jinbo, Wang, Wei, Huo, Yi, Zheng, Guoxu, Wu, Jieheng, Li, Yufang, Yang, Angang, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827631/
https://www.ncbi.nlm.nih.gov/pubmed/29457966
http://dx.doi.org/10.12659/MSM.906020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827631/
https://www.ncbi.nlm.nih.gov/pubmed/29457966
http://dx.doi.org/10.12659/MSM.906020

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