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Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model

Opioid analgesics are frequently prescribed in the United States and worldwide. However, serious comorbidities, such as dependence, tolerance, immunosuppression and gastrointestinal disorders limit their long-term use. In the current study, a morphine-murine model was used to investigate the role of...

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Detalles Bibliográficos
Autores principales: Wang, Fuyuan, Meng, Jingjing, Zhang, Li, Johnson, Timothy, Chen, Chi, Roy, Sabita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827657/
https://www.ncbi.nlm.nih.gov/pubmed/29483538
http://dx.doi.org/10.1038/s41598-018-21915-8