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Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model
Opioid analgesics are frequently prescribed in the United States and worldwide. However, serious comorbidities, such as dependence, tolerance, immunosuppression and gastrointestinal disorders limit their long-term use. In the current study, a morphine-murine model was used to investigate the role of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827657/ https://www.ncbi.nlm.nih.gov/pubmed/29483538 http://dx.doi.org/10.1038/s41598-018-21915-8 |