Oligonucleotide conjugated multi-functional adeno-associated viruses

Recombinant adeno-associated viruses (AAVs) are among the most commonly used vehicles for in vivo gene delivery. However, their tropism is limited, and additionally their efficacy can be negatively affected by prevalence of neutralizing antibodies in sera. Methodologies to systematically engineer AA...

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Detalles Bibliográficos
Autores principales: Katrekar, Dhruva, Moreno, Ana M., Chen, Genghao, Worlikar, Atharv, Mali, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827683/
https://www.ncbi.nlm.nih.gov/pubmed/29483550
http://dx.doi.org/10.1038/s41598-018-21742-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827683/
https://www.ncbi.nlm.nih.gov/pubmed/29483550
http://dx.doi.org/10.1038/s41598-018-21742-x

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