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Vasopressin-secreting neurons derived from human embryonic stem cells through specific induction of dorsal hypothalamic progenitors

Arginine-vasopressin (AVP) neurons exist in the hypothalamus, a major region of the diencephalon, and play an essential role in water balance. Here, we established the differentiation method for AVP-secreting neurons from human embryonic stem cells (hESCs) by recapitulating in vitro the in vivo embr...

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Detalles Bibliográficos
Autores principales: Ogawa, Koichiro, Suga, Hidetaka, Ozone, Chikafumi, Sakakibara, Mayu, Yamada, Tomiko, Kano, Mayuko, Mitsumoto, Kazuki, Kasai, Takatoshi, Kodani, Yu, Nagasaki, Hiroshi, Yamamoto, Naoki, Hagiwara, Daisuke, Goto, Motomitsu, Banno, Ryoichi, Sugimura, Yoshihisa, Arima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827757/
https://www.ncbi.nlm.nih.gov/pubmed/29483626
http://dx.doi.org/10.1038/s41598-018-22053-x