Cargando…

Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL

Altered lipid metabolism and aberrant protein translation are strongly associated with cancerous outgrowth; however, the inter-regulation of these key processes is still underexplored in diffuse large B-cell lymphoma (DLBCL). Although fatty acid synthase (FASN) activity is reported to positively cor...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapadia, Bandish, Nanaji, Nahid M., Bhalla, Kavita, Bhandary, Binny, Lapidus, Rena, Beheshti, Afshin, Evens, Andrew M., Gartenhaus, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827760/
https://www.ncbi.nlm.nih.gov/pubmed/29483509
http://dx.doi.org/10.1038/s41467-018-03028-y