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Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL
Altered lipid metabolism and aberrant protein translation are strongly associated with cancerous outgrowth; however, the inter-regulation of these key processes is still underexplored in diffuse large B-cell lymphoma (DLBCL). Although fatty acid synthase (FASN) activity is reported to positively cor...
Autores principales: | Kapadia, Bandish, Nanaji, Nahid M., Bhalla, Kavita, Bhandary, Binny, Lapidus, Rena, Beheshti, Afshin, Evens, Andrew M., Gartenhaus, Ronald B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827760/ https://www.ncbi.nlm.nih.gov/pubmed/29483509 http://dx.doi.org/10.1038/s41467-018-03028-y |
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