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Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

Traumatic brain injury (TBI) induces a wide variety of cellular and molecular changes that can continue for days to weeks to months, leading to functional impairments. Currently, there are no pharmacotherapies in clinical use that favorably modify the post-TBI outcome, due in part to limited underst...

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Detalles Bibliográficos
Autores principales: Lipponen, Anssi, El-Osta, Assam, Kaspi, Antony, Ziemann, Mark, Khurana, Ishant, KN, Harikrishnan, Navarro-Ferrandis, Vicente, Puhakka, Noora, Paananen, Jussi, Pitkänen, Asla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828078/
https://www.ncbi.nlm.nih.gov/pubmed/29482641
http://dx.doi.org/10.1186/s40478-018-0519-z