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Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics

BACKGROUND: Protein kinase C ζ (PKCζ), an isoform of the atypical protein kinase C, is a pivotal regulator in cancer. However, the molecular and cellular mechanisms whereby PKCζ regulates tumorigenesis and metastasis are still not fully understood. In this study, proteomics and bioinformatics analys...

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Detalles Bibliográficos
Autores principales: Hou, Chunyu, Li, Yuan, Liu, Huiqin, Dang, Mengjiao, Qin, Guoxuan, Zhang, Ning, Chen, Ruibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828088/
https://www.ncbi.nlm.nih.gov/pubmed/29491746
http://dx.doi.org/10.1186/s12953-018-0134-8