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Zoledronic acid increases the prevalence of medication-related osteonecrosis of the jaw in a dose dependent manner in rice rats (Oryzomys palustris) with localized periodontitis

OBJECTIVE: Investigate role of dose/duration of zoledronic acid (ZOL), a powerful anti-resorptive (pAR), on prevalence of medication-related osteonecrosis of the jaw (MRONJ) in rice rats (Oryzomys palustris), a species with natural susceptibility to food impaction-induced localized periodontitis (FI...

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Detalles Bibliográficos
Autores principales: Messer, J.G., Mendieta Calle, J.L., Jiron, J.M., Castillo, E.J., Van Poznak, C., Bhattacharyya, N., Kimmel, D.B., Aguirre, J.I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828169/
https://www.ncbi.nlm.nih.gov/pubmed/29289789
http://dx.doi.org/10.1016/j.bone.2017.12.025