Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors

A suitable clinical-grade platform is required for detection of somatic mutations with high sensitivity in cell-free DNA (cfDNA) of patients with solid tumors. In this study, we evaluated in parallel ultra-deep NGS with MassARRAY and allele-specific droplet digital PCR (ddPCR) for cfDNA genotyping a...

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Detalles Bibliográficos
Autores principales: Mehrotra, Meenakshi, Singh, Rajesh R., Loghavi, Sanam, Duose, Dzifa Yawa, Barkoh, Bedia A., Behrens, Carmen, Patel, Keyur P., Routbort, Mark J., Kopetz, Scott, Broaddus, Russell R., Medeiros, L. Jeffrey, Wistuba, Ignacio I., Luthra, Rajyalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828199/
https://www.ncbi.nlm.nih.gov/pubmed/29535804
http://dx.doi.org/10.18632/oncotarget.21982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828199/
https://www.ncbi.nlm.nih.gov/pubmed/29535804
http://dx.doi.org/10.18632/oncotarget.21982

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