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Bevacizumab-based first-line chemotherapy in elderly patients with metastatic colorectal cancer: an individual patient data based meta-analysis

BACKGROUND: The aim of this meta-analysis was to evaluate efficacy and safety of first-line chemotherapy with or without a monoclonal antibody in elderly patients (≥ 70 years) with metastatic colorectal cancer (mCRC), since they are frequently underrepresented in clinical trials. RESULTS: Individual...

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Detalles Bibliográficos
Autores principales: Koch, Christine, Schwing, Anna M., Herrmann, Eva, Borner, Markus, Diaz-Rubio, Eduardo, Dotan, Efrat, Feliu, Jaime, Okita, Natsuko, Souglakos, John, Arkenau, Hendrik T., Porschen, Rainer, Koopman, Miriam, Punt, Cornelis J.A., de Gramont, Aimery, Tournigand, Christophe, Zeuzem, Stefan, Trojan, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828201/
https://www.ncbi.nlm.nih.gov/pubmed/29535805
http://dx.doi.org/10.18632/oncotarget.23475