Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers

Papillary renal cell carcinomas (PRCC) are a histologically and genetically heterogeneous group of tumors that represent 15–20% of all kidney neoplasms and may require diverse therapeutic approaches. Alteration of the NF2 tumor suppressor gene, encoding a key regulator of the Hippo signaling pathway...

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Detalles Bibliográficos
Autores principales: Sourbier, Carole, Liao, Pei-Jyun, Ricketts, Christopher J., Wei, Darmood, Yang, Youfeng, Baranes, Sarah M., Gibbs, Benjamin K., Ohanjanian, Lernik, Spencer Krane, L., Scroggins, Bradley T., Keith Killian, J., Wei, Ming-Hui, Kijima, Toshiki, Meltzer, Paul S., Citrin, Deborah E., Neckers, Len, Vocke, Cathy D., Marston Linehan, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828210/
https://www.ncbi.nlm.nih.gov/pubmed/29535838
http://dx.doi.org/10.18632/oncotarget.24112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828210/
https://www.ncbi.nlm.nih.gov/pubmed/29535838
http://dx.doi.org/10.18632/oncotarget.24112

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