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The crosstalk between breast carcinoma-associated fibroblasts and cancer cells promotes RhoA-dependent invasion via IGF-1 and PAI-1

Carcinoma-associated fibroblasts (CAFs) can remodel the extracellular matrix to promote cancer cell invasion, but the paracrine signaling between CAFs and cancer cells that regulates tumor cell migration remains to be identified. To determine how the interaction between CAFs and cancer cells modulat...

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Detalles Bibliográficos
Autores principales: Daubriac, Julien, Han, Shiwei, Grahovac, Jelena, Smith, Eve, Hosein, Abdel, Buchanan, Marguerite, Basik, Mark, Boucher, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828213/
https://www.ncbi.nlm.nih.gov/pubmed/29535813
http://dx.doi.org/10.18632/oncotarget.23735