Severe hypoxia selects hematopoietic progenitors with stem cell potential from primary Myelodysplastic syndrome bone marrow cell cultures

Myelodysplastic Syndromes (MDS) are clonal neoplasms where stem/progenitor cells endowed with self-renewal and capable of perpetuating the disease have been demonstrated. It is known that oxygen tension plays a key role in driving normal hematopoiesis and that hematopoietic stem cells are maintained...

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Detalles Bibliográficos
Autores principales: Masala, Erico, Valencia-Martinez, Ana, Pillozzi, Serena, Rondelli, Tommaso, Brogi, Alice, Sanna, Alessandro, Gozzini, Antonella, Arcangeli, Annarosa, Sbarba, Persio Dello, Santini, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828219/
https://www.ncbi.nlm.nih.gov/pubmed/29535827
http://dx.doi.org/10.18632/oncotarget.24302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828219/
https://www.ncbi.nlm.nih.gov/pubmed/29535827
http://dx.doi.org/10.18632/oncotarget.24302

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