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NoLogo: a new statistical model highlights the diversity and suggests new classes of Crm1-dependent nuclear export signals

BACKGROUND: Crm1-dependent Nuclear Export Signals (NESs) are clusters of alternating hydrophobic and non-hydrophobic amino acid residues between 10 to 15 amino acids in length. NESs were largely thought to follow simple consensus patterns, based on which they were categorized into 6–10 classes. Howe...

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Detalles Bibliográficos
Autores principales: Liku, Muluye E., Legere, Elizabeth-Ann, Moses, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828312/
https://www.ncbi.nlm.nih.gov/pubmed/29482494
http://dx.doi.org/10.1186/s12859-018-2076-7