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The chromatin remodeling subunit Baf200 promotes normal hematopoiesis and inhibits leukemogenesis

BACKGROUND: Adenosine triphosphate (ATP)-dependent chromatin remodeling SWI/SNF-like BAF and PBAF complexes have been implicated in the regulation of stem cell function and cancers. Several subunits of BAF or PBAF, including BRG1, BAF53a, BAF45a, BAF180, and BAF250a, are known to be involved in hema...

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Detalles Bibliográficos
Autores principales: Liu, Lulu, Wan, Xiaoling, Zhou, Peipei, Zhou, Xiaoyuan, Zhang, Wei, Hui, Xinhui, Yuan, Xiujie, Ding, Xiaodan, Zhu, Ruihong, Meng, Guangxun, Xiao, Hui, Ma, Feng, Huang, He, Song, Xianmin, Zhou, Bin, Xiong, Sidong, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828314/
https://www.ncbi.nlm.nih.gov/pubmed/29482581
http://dx.doi.org/10.1186/s13045-018-0567-7