Frequency of BRCA1 and BRCA2 causative founder variants in ovarian cancer patients in South-East Poland

BACKGROUND: Causative variants in BRCA1 and BRCA2 are well-established risk factors for breast and ovarian cancer. In Poland, the causative founder variants in the BRCA1 are responsible for a significant proportion of ovarian cancer cases, however, regional differences in the frequencies of various...

Descripción completa

Detalles Bibliográficos
Autores principales: Kluz, Tomasz, Jasiewicz, Andrzej, Marczyk, Elżbieta, Jach, Robert, Jakubowska, Anna, Lubiński, Jan, Narod, Steven A., Gronwald, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828315/
https://www.ncbi.nlm.nih.gov/pubmed/29492181
http://dx.doi.org/10.1186/s13053-018-0089-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828315/
https://www.ncbi.nlm.nih.gov/pubmed/29492181
http://dx.doi.org/10.1186/s13053-018-0089-x

Ejemplares similares