Independent functions of DNMT1 and USP7 at replication foci

BACKGROUND: It has been reported that USP7 (ubiquitin-specific protease 7) prevents ubiquitylation and degradation of DNA methyltransferase 1 (DNMT1) by direct binding of USP7 to the glycine-lysine (GK) repeats that join the N-terminal regulatory domain of DNMT1 to the C-terminal methyltransferase d...

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Detalles Bibliográficos
Autores principales: Yarychkivska, Olya, Tavana, Omid, Gu, Wei, Bestor, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828336/
https://www.ncbi.nlm.nih.gov/pubmed/29482658
http://dx.doi.org/10.1186/s13072-018-0179-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828336/
https://www.ncbi.nlm.nih.gov/pubmed/29482658
http://dx.doi.org/10.1186/s13072-018-0179-z

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