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Aggregate Size Dependence of Amyloid Adsorption onto Charged Interfaces

[Image: see text] Amyloid aggregates are associated with a range of human neurodegenerative disorders, and it has been shown that neurotoxicity is dependent on aggregate size. Combining molecular simulation with analytical theory, a predictive model is proposed for the adsorption of amyloid aggregat...

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Detalles Bibliográficos
Autores principales: Tesei, Giulio, Hellstrand, Erik, Sanagavarapu, Kalyani, Linse, Sara, Sparr, Emma, Vácha, Robert, Lund, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828364/
https://www.ncbi.nlm.nih.gov/pubmed/29284092
http://dx.doi.org/10.1021/acs.langmuir.7b03155